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Product Name | 7-keto Cholesterol |
Description | A bioactive oxysterol; a major oxysterol component of oxidized LDL; produced by oxidation of cholesterol via ethanol-mediated lipid peroxidation or photodamage as well as oxidation of 7-dehydro cholesterol by CYP7A1; inhibits CYP7A1 (IC50 = ~1 µM); induces activation and chemotaxis of retinal microglia as well as polarization to a pro-inflammatory state; increases ocular levels of VEGF, IL-1β, and GRO/KC, macrophage infiltration, and neovascularization in rat eye; levels are increased in lipid deposits in a variety of chronic diseases, |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 7-oxo Cholesterol|SC-4722|Δ5-Cholesterol-3β-ol-7-one |
Gene, Accession, CAS # | CAS: 566-28-9 |
Catalog # | 16339-50 |
Price | $412.00 |
Order / More Info | 7-keto Cholesterol from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |