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Product Name | IRAK4 Inhibitor 28 |
Description | An IRAK4 inhibitor (IC50 = 0.005 µM); selective for IRAK4 over IRAK1, Clk1, and Clk3 (IC50s = 0.023, 0.05, and >1 µM, respectively) but does inhibit Clk2, Clk4, and haspin (IC50s = 0.005, 0.008, and 0.004 µM, respectively); inhibits IκBα phosphorylation in OCI-LY10 DLBCL cells from 0.12-3.3 µM; reduces tumor volume in an OCI-LY10 mouse xenograft model at 12.5 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | IRAK-IN-28 |
Gene, Accession, CAS # | CAS: 2196204-23-4 |
Catalog # | 40167-1 |
Price | $57.00 |
Order / More Info | IRAK4 Inhibitor 28 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |