SEL120-34A from CAYMAN CHEMICAL COMPANY

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Product NameSEL120-34A
DescriptionA dual inhibitor of Cdk8 and Cdk19 (IC50s = 4.4 and 10.4 nM, respectively); selective for Cdk8 and Cdk19 over a panel of CDK/cyclin complexes at 1 µM; inhibits IFN-γ-induced phosphorylation of STAT1 in HCT116 colon cancer cells at 0.1-5 µM; inhibits proliferation of MOLM-16, MV4-11, and KG-1 cells (GI50s = <1 µM); reduces tumor growth in a KG-1 mouse xenograft model at 60 mg/kg
Size500 µg
Concentrationn/a
Applicationsn/a
Other Names1609522-33-9 SEL12034A SEL-12034A 34-A Cdk-8 19 IFNγ STAT-1 HCT-116 MOLM16 MV411 KG1
Gene, Accession, CAS #CAS: 1609452-30-3
Catalog #27906-500
Price$32.00
Order / More InfoSEL120-34A from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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http://www.caymanchem.com

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