GDC-0879 from CAYMAN CHEMICAL COMPANY
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| Product Name | GDC-0879 |
| Description | An inhibitor of B-RafV600E (IC50 = 0.13 nM for human recombinant enzyme); selective for B-RafV600E over a panel of 140 kinases at 1 µM; inhibits phosphorylation of ERK in MALME-3M cells (IC50 = 63 nM) as well as phosphorylation of MEK1 in COLO 205 and A375 cells that express B-RafV600E (IC50s = 29 and 59 nM, respectively); inhibits tumor growth in an A375 mouse xenograft model from 15-200 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | GDC0879 MALME3M BRaf V600E5 MEK-1 COLO205 A-375 BRafV600E5 AR 00341677 GDC089 089 |
| Gene, Accession, CAS # | CAS: 905281-76-7 |
| Catalog # | 16993-5 |
| Price | $116.00 |
| Order / More Info | GDC-0879 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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