MSDC-0602 from CAYMAN CHEMICAL COMPANY
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| Product Name | MSDC-0602 |
| Description | A PPARγ-sparing thiazolidinedione derivative; binds only weakly to PPARγ (IC50 = 18.25 µM) and induces minimal activation of a Gal4-PPARγ reporter construct at 50 µM; decreases the pyruvate-induced oxygen consumption rate in control mitochondria but not in LS-Mpc2-/- mitochondria; reduces body weight gain and adiposity, as well as increases intrascapular BAT mass in a mouse model of NASH; reverses hepatic fibrosis and stellate cell fibrinogenesis in a mouse model of NASH; decreases plasma glucose, triglyceride, and cholesterol levels in ob/ob mice and increases insulin sensitivity in the striatal muscle, adipose tissue, and liver of diet-induced obese mice |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 1314533-27-1 MS DC MSDC0602 06 02 PPAR γ Gal 4 Gal4PPARγ Gal4PPAR LSMpc2 Mpc transfat transfructose transcholesterol ob NA SH |
| Gene, Accession, CAS # | CAS: 1133819-87-0 |
| Catalog # | 27829-50 |
| Price | $363.00 |
| Order / More Info | MSDC-0602 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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