NVP-BAG956 from CAYMAN CHEMICAL COMPANY
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| Product Name | NVP-BAG956 |
| Description | A dual PDK1 and class I PI3K inhibitor (IC50s = 245, 56, 446, 35, and 117 nM for PDK1, p110α, p110β, p110δ, and p110γ, respectively); inhibits phosphorylation of T308-PKB (IC50 = 45 nM) in and proliferation of U87MG cells (EC50 = 143 nM); induces cell cycle arrest at the G1 phase in MOLM-14 cells and reduces colony formation by patient-derived AML cells; reduces tumor burden in mice injected with 32D.p210-luc+cells when administered in combination with everolimus |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | BAG956 |
| Gene, Accession, CAS # | CAS: 853910-02-8 |
| Catalog # | 24195-1 |
| Price | $37.00 |
| Order / More Info | NVP-BAG956 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY