GDC-0575 from CAYMAN CHEMICAL COMPANY
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| Product Name | GDC-0575 |
| Description | A Chk1 inhibitor (IC50 = 1.2 nM); >30-fold selective for Chk1 over a panel of more than 450 wild-type and mutant kinases; enhances cytarabine-induced apoptosis in HL-60, KG-1, U937, and ML-1 AML cells; nearly completely eliminates tumor burden in AML PDX mouse models at 7.5 mg/kg in combination with cytarabine |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Chk HL60 KG1 U-937 ML1 GDC0575 |
| Gene, Accession, CAS # | CAS: 1196541-47-5 |
| Catalog # | 34300-25 |
| Price | $571.00 |
| Order / More Info | GDC-0575 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY