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Product Name | ZLN005 |
Description | A small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 µM; 15 mg/kg/day administered to diabetic db/db mice improved glucose tolerance, pyruvate tolerance, and insulin sensitivity |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | metabolic syndromes PGC-1α PGC-1a PGC-1.alpha. PGC-1alpha PGC1α PGC1a PGC1.alpha. PGC1alpha PGCs peroxisomes proliferator-activated proliferators activated receptors receptor-γ receptor-g receptor-gamma receptor-.gamma. coactivator-1α coactivator-1a coactivator-1alpha coactivator-1.alpha. metabolisms type 2 diabetes ZLN-005 ZLNs 005 stimulates stimulations express expressions downstreams genes skeletal muscles cells glucose fatty acids oxidations diabetics diabetes tolerances pyruvates insulin coactivators tissue-specific tissues specific inducible transcriptions factors transcriptional nuclear energy metabolisms hepatic livers glucogenesis cholesterols homeostasis small molecules db/db mice mouse fats |
Gene, Accession, CAS # | CAS: 49671-76-3 |
Catalog # | 14121-50 |
Price | $213.00 |
Order / More Info | ZLN005 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |