GSK1059615 from CAYMAN CHEMICAL COMPANY
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| Product Name | GSK1059615 |
| Description | A potent, reversible, ATP-competitive, thiazolidinedione inhibitor of PI3Kα (IC50 = 2 nM) and the common activating mutants of p100α (E542K, E545K, and H1047R) found in cancer; prevents proliferation in BT474 tumor xenografts and reduces MAPK signaling with twice daily dosing at 25 mg/kg |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Phosphatidylinositols PI 3-kinases α PI3Ks PI3Kα PI3Ka PI3K.alpha. inhibits inhibitors inhibition thiazolidinediones cells growth human cancers ATP-competitive p110α p110.alpha. p110a E542K E545K H1047R BT474 tumors xenografts MAPKs signaling biology signals transductions 1356195-42-0 1497419-94-9 GSK 1059615 GSK-615 |
| Gene, Accession, CAS # | CAS: 958852-01-2 |
| Catalog # | 11569-50 |
| Price | $456.00 |
| Order / More Info | GSK1059615 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
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Ann Arbor MI 48108
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