CA-074 from CAYMAN CHEMICAL COMPANY
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| Product Name | CA-074 |
| Description | A selective cathepsin B inhibitor (Kis = 0.0087, 75, and 233 µM for rat cathepsin B, H, and L, respectively); inhibits degradation of DQ-collagen IV and DQ-collagen I in 4T1.2 breast cancer cells; reduces the number of lung and bone metastases in a 4T1.2 murine mammary cancer model at 50 mg/kg; reduces mercury-induced increases in expression of TNF-α, IL-1β, and the inflammasome component NRLP3 and decreases the severity of mercury-induced skin induration in mice at 0.1 and 0.2 mg/kg; reduces ischemia-induced hippocampal neuron cell death in monkeys |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CA074 74 TNFα IL1β NRLP-3 |
| Gene, Accession, CAS # | CAS: 134448-10-5 |
| Catalog # | 24679-1 |
| Price | $176.00 |
| Order / More Info | CA-074 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY