GDC-0326 from CAYMAN CHEMICAL COMPANY
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| Product Name | GDC-0326 |
| Description | A selective inhibitor of PI3Kα (Ki = 0.2 nM); is 133-, 20-, and 51-fold selective for PI3Kα over PI3Kβ, PI3Kδ, and PI3Kγ, respectively; inhibits proliferation of MCF7-neo/HER2 and PC3 cells (EC50s = 0.1 and 2.2 µM, respectively); induces tumor regression in a KPL-4 mouse xenograft model at 6.25 mg/kg; reduces tumor growth, tumor vasculature, and the number of liver and lymph node metastases in the RIP1-Tag2 transgenic mouse model of pancreatic neuroendocrine tumors |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | GDC0326 Phosphoinositide HER-2 MCF-7 PC-3 KPL4 PI3K-α PI3-K PI-3K PI3-Kα |
| Gene, Accession, CAS # | CAS: 1282514-88-8 |
| Catalog # | 19241-5 |
| Price | $131.00 |
| Order / More Info | GDC-0326 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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