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Product Name | Methylcarbamyl PAF C-16 |
Description | Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH.{613,4944} It is nearly equipotent with PAF C-16 in its ability to induce platelet aggregation both in isolated platelets and in PRP.{613} In NRK-49 cells overexpressing the PAF receptor, both PAF C-16 and methylcarbamyl PAF C-16 cause the induction of c-myc and c-fos and the activation of MAPK.{4944} Methylcarbamyl PAF C-16 induces G1 phase cell cycle arrest, suggesting a potential role for PAF in the inhibition of oncogenic transformation.{4944} |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | PAFs platelet-activating factors analogs agonists |
Gene, Accession, CAS # | CAS: 91575-58-5 |
Catalog # | 60908-1 |
Price | $36.00 |
Order / More Info | Methylcarbamyl PAF C-16 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |