GCN2iB from CAYMAN CHEMICAL COMPANY
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| Product Name | GCN2iB |
| Description | A GCN2 inhibitor (IC50 = 2.4 nM); selective for GCN2 over a panel of 465 kinases but does inhibit MAP2K5, EIF2AK2, and MAP3K20 at 1 µM; in combination with L-aspariginase reduces the viability of MEFs at 1 µM; decreases the levels of ATF4 and phosphorylated GCN2 in combination with L-aspariginase in CCRF CEM leukemia cells at 0.4 µM;, reduces tumor volume in combination with L-aspariginase in CCRF CEM and MV4-11 leukemia mouse xenograft models at 10 mg/kg twice per day |
| Size | 500 µg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | GCN2-iB GCN-2iB 2 MAP-2K5 3K20 EIF-2AK2 ATF-4 MV411 |
| Gene, Accession, CAS # | CAS: 2183470-12-2 |
| Catalog # | 35897-500 |
| Price | $49.00 |
| Order / More Info | GCN2iB from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY