Verdinexor from CAYMAN CHEMICAL COMPANY

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Product NameVerdinexor
DescriptionAn inhibitor of XPO1/CRM1 with anticancer and antiviral activities; inhibits the growth of OCI-Ly3, OCI-Ly10, and CLBL1 DLBCL cells (IC50s = 2.1, 41.8, and 8.5 nM, respectively); inhibits XPO1/CRM1-mediated nuclear transport of RSV M protein at >1 µM; reduces RSV A2 replication (IC50 = 0.96 µM) without affecting viability of A549 cells (CC50 = >38 µM); reduces virus shedding, pulmonary TNF-α, IL-6, MCP01, and IFN-γ expression, and leukocyte infiltration into the bronchoalveolar space in a mouse model of influenza A viral infection at 20 mg/kg
Size5 mg
Concentrationn/a
Applicationsn/a
Other NamesKPT-335
Gene, Accession, CAS #CAS: 1392136-43-4
Catalog #26171-5
Price$120.00
Order / More InfoVerdinexor from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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