Itraconazole from CAYMAN CHEMICAL COMPANY
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| Product Name | Itraconazole |
| Description | An antifungal agent and hedgehog pathway inhibitor; inhibits hedgehog signaling (IC50 = 0.8 µM); binds to 14-α sterol demethylase/CYP51 isoform B (Kd = 31 nM for A. fumigatus enzyme expressed in E. coli); inhibits ergosterol biosynthesis in C. neoformans (IC50 = 6 nM after 16 hours); inhibits C. neoformans growth by 50% at 3.2 nM; suppresses growth of medulloblastomas in a Ptch+/-p53-/- mouse allograft model at 100 mg/kg twice daily; reduces viral titers of several enteroviruses in infected cells from 1.25-100 µM |
| Size | 250 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | anti-fungal CYP-51 AF-51-B Aspergillus Escherichia Cryptococcus NIHT3T3 p-53 |
| Gene, Accession, CAS # | CAS: 84625-61-6 |
| Catalog # | 13288-250 |
| Price | $225.00 |
| Order / More Info | Itraconazole from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY