JTE-907 from CAYMAN CHEMICAL COMPANY
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| Product Name | JTE-907 |
| Description | A CB2 receptor inverse agonist; selective for CB2 over CB1 receptors (Kis = 35.9 and 2,370 nM, respectively, for the human receptors); increases forskolin-induced cAMP production in CHO cells expressing human or mouse CB2 receptors; promotes the differentiation of isolated mouse splenic CD4+ T cells into Tregs at 100 nM; decreases disease severity in a mouse model of DNBS-induced IBD; inhibits spontaneous scratching in a mouse model of chronic dermatitis at 1 and 10 mg/kg; reduces carrageenan-induced paw edema in mice (ED50 = 0.05 mg/kg); bilateral injection into the anterior bed nucleus of the stria terminalis decreases the percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiety-like behavior, at 25 pmol/animal |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | JTE907 CB-1 2 chinese hamster ovary CD 4+ |
| Gene, Accession, CAS # | CAS: 282089-49-0 |
| Catalog # | 10009857-1 |
| Price | $62.00 |
| Order / More Info | JTE-907 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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