Astilbin from CAYMAN CHEMICAL COMPANY
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| Product Name | Astilbin |
| Description | A flavonoid with diverse biological activities; inhibits cisplatin-induced increases in apoptosis and ROS in HEK293 cells at 200 µM; increases renal GSH levels and SOD and catalase activity and reduces serum creatinine and BUN levels, renal IL-1β, IL-6, and TNF-α levels, apoptosis in kidney tissue, and kidney injury in a mouse model of cisplatin-induced nephrotoxicity at 50 mg/kg; reduces loss of dopaminergic neurons in the substantia nigra and increases striatal GSH levels and SOD activity in a mouse model of MPTP-induced Parkinson's disease at 50 mg/kg per day; reduces motor deficits in a mouse model of Parkinson's disease; reduces cell viability of MDA-MB-231 and MCF-7 cells (IC50s = 167.9 and 191.6 µM, respectively), as well as inhibits migration and increases apoptosis at 50 and 200 µM; reduces tumor growth in an MCF-7 mouse xenograft model at 20 mg/kg every other day for 14 days |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Taxifolin 3-O-rhamnoside |
| Gene, Accession, CAS # | CAS: 29838-67-3 |
| Catalog # | 28267-10 |
| Price | $109.00 |
| Order / More Info | Astilbin from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY