Nargenicin from CAYMAN CHEMICAL COMPANY
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| Product Name | Nargenicin |
| Description | A macrolide antibiotic that is selective for S. aureus, MRSA, and M. luteus (MICs = 0.6, 0.3, and 2.5 µg/ml, respectively) over a panel of 11 Gram-positive and Gram-negative bacteria (MICs = >80 µg/ml); inhibits S. aureus DnaE in the presence of DNase I-activated DNA and E. coli DnaE at 0.00001-0.1 and 0.01-100 µg/mL, respectively; inhibits LPS-induced cytokine expression and nitric oxide production in murine BV-2 cells at 1 µM; reduces HL-60 cell proliferation increases cell differentiation when used in combination with 1,25-dihydroxyvitamin D3 or all-trans retinoic acid at 200 µM; reduces the number of CFUs in infected kidneys by 100,000-fold in a murine model of S. aureus infection at 50 mg/kg, p.o |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Antibiotic 47444|CP 47,444|NSC 355066 |
| Gene, Accession, CAS # | CAS: 70695-02-2 |
| Catalog # | 25456-5 |
| Price | $738.00 |
| Order / More Info | Nargenicin from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY