Edit |   |
---|---|
Product Name | U-92016A |
Description | A 5-HT1A receptor agonist (Ki = 0.4 nM); selective for 5-HT1A over 5-HT1D, 5-HT2, dopamine D1 and D2, and α1- and α2-adrenergic receptors (Kis = 7.7, >1,000, >1,000, 36, >1,000, and >1,000 nM, respectively); inhibits forskolin-stimulated cAMP synthesis in CHO cells transfected with human 5-HT1A; induces hypothermia in mice (ED50 = 0.041 mg/kg); induces 5-HT syndrome as well as decreases accumulation of 5-HT and dopamine in rats (5 mg/kg); decreases arterial blood pressure and heart rate in a dose-dependent manner in spontaneously hypertensive rats; reverses isolation-induced aggression in mice, |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 136924-88-4 U92016A 5HT 5HT-1D 5HT2 1A 5HT1A |
Gene, Accession, CAS # | CAS: 149654-41-1 |
Catalog # | 23807-5 |
Price | $139.00 |
Order / More Info | U-92016A from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |