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Product Name | GSK2033 |
Description | An antagonist of LXRα and LXRβ (IC50s = 0.1 and 0.398 µM, respectively); inhibits LXR agonist-induced and basal expression of ABCA1 and SREBP-1c in THP-1 and HepG2 cells; binds promiscuously to a variety of nuclear receptors including RORγ, RXRα, ERα, and ERβ in a nuclear receptor specificity assay in HEK293 cells; induces the expression of fatty acid synthase and SREBP-1 in a mouse model of NAFLD |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | GSK-2033 LXR-α β ABCA-1 SREBP1c THP1 HepG-2 ROR-γ α ER-α β RXR |
Gene, Accession, CAS # | CAS: 1221277-90-2 |
Catalog # | 25443-10 |
Price | $230.00 |
Order / More Info | GSK2033 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |