NF449 (sodium salt) from CAYMAN CHEMICAL COMPANY
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| Product Name | NF449 (sodium salt) |
| Description | An analog of suramin that selectively inhibits P2X1 receptors (pIC50 = 6.3); selectively antagonizes the Gsα-subunit G protein, which suppresses the association rate of GTPγS binding to Gsα-s, inhibits the stimulation of adenylyl cyclase activity, and blocks G protein coupling to certain GPCRs |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 389142-38-5 suramin inhibitors P2X1 platelets aggregations thromboembolism G-proteins antagonists inhibits inhibitions G proteins Gproteins NF-449 NFs 449 analogs 11126 purinergic potent potency decreases intravascular platelets aggregation mouse mice models systemic antagonism Gsa Gsα Gsalpha Gs.alpha. subunits adenylyl cyclase activity GPCRs P2Y1 P2Y2 P2Y11 selective supresses supression associations rates binding binds stimulation stimulates blocks coupling active |
| Gene, Accession, CAS # | CAS: 627034-85-9 |
| Catalog # | 13324-50 |
| Price | $704.00 |
| Order / More Info | NF449 (sodium salt) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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