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Product Name | Klotho-derived Peptide 1 (56-87) (human) (trifluoroacetate salt) |
Description | A TGF-β disrupting peptide; binds to ALK5 and TGFBR2 (Kds = 1.41 and 14.6 µM, respectively); preincubation inhibits TGF-β-induced increases in fibronectin and α-SMA levels in NRK-49F cells at 10 µg/ml; selectively localizes to damaged kidneys and reduces serum creatine and blood urea nitrogen levels, markers of kidney function, as well as reduces kidney fibrosis, in mouse models of UUO and unilateral ischemia-reperfusion injury-induced renal fibrosis at 1 mg/kg per day |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | KP1 (56-87) |
Gene, Accession, CAS # | n/a |
Catalog # | 38166-1 |
Price | $88.00 |
Order / More Info | Klotho-derived Peptide 1 (56-87) (human) (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |