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Product Name | CP 91,149 |
Description | An inhibitor of LGPa, MGPa, and MGPb (IC50s = 0.13, 0.2, and 0.3 µM, respectively, in the presence of glucose); inhibits glucagon-stimulated glycogenolysis in primary human hepatocytes (IC50 = 2.1 µM) and increases glycogen synthesis in rat hepatocytes at a concentration of 2.5 µM in the presence of 5 mM glucose; inhibits brain GP (IC50 = 0.5 µM) and glycogen accumulation and proliferation of A549 NSCLC cells that express endogenous brain GP (30 µM); lowers plasma glucose level in diabetic ob/ob mice within 3 hours of administration without producing hypoglycemia, but has no effect on normoglycemic, non-diabetic mice (25 mg/kg, p.o.) |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 91149 CP91149 |
Gene, Accession, CAS # | CAS: 186392-40-5 |
Catalog # | 17709-5 |
Price | $62.00 |
Order / More Info | CP 91,149 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |