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Product Name | (R)-ErSO |
Description | An activator of the anticipatory unfolded protein response; inhibits protein synthesis and induces intracellular ATP depletion in T47D cells at 1 µM ; increases levels of phosphorylated EIF2AK3, eIF2α, and AMPK in T47D cells at 1 µM; cytotoxic to T47D, TYS, BT474, and ZR-75-1 ERα-positive breast cancer cells (IC50s = 16.4, 11.1, 26.9, and 42.8 nM, respectively); induces tumor regression in an MCF-7 mouse xenograft model at 40 mg/kg; induces tumor regression in an ST941/HI PDX mouse model |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ErSO |
Gene, Accession, CAS # | CAS: 2407860-35-7 |
Catalog # | 35684-10 |
Price | $648.00 |
Order / More Info | (R)-ErSO from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |