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Product Name | DWK-1339 |
Description | An inhibitor of amyloid-β aggregation; inhibits aggregation of monomeric Aβ42 and induces disaggregation of Aβ42 fibrils in vitro from 3.1-50 µM; reduces Aβ42-induced toxicity in HT22 cells at 10 µM; increases step-through latency in a passive avoidance test and increases spontaneous alteration in the Y-maze compared with vehicle control mice in a mouse model of Aβ42-induced acute Alzheimer's disease at 10 mg/kg; decreases brain levels of Aβ42 and increases spontaneous alteration in the Y-maze in the APP/PS1 transgenic mouse model of Alzheimer's disease |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MDR-1339 |
Gene, Accession, CAS # | CAS: 1018946-38-7 |
Catalog # | 27642-1 |
Price | $230.00 |
Order / More Info | DWK-1339 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |