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Product Name | IPN60090 |
Description | A GLS1 inhibitor (IC50 = 0.031 µM for the glutaminase C isoform); selective for GLS1 over GLS2 (IC50 = >50 µM), as well as panels of 80 ion channels and receptors and 97 kinases at 10 µM; binds to ZSWIM4 (Kd = 2.98 µM); decreases the viability of A549 cells (IC50 = 26 nM); decreases tumor weight and volume in a SKOV3 mouse xenograft model at 30 mg/kg, p.o., in combination with carboplatin,, |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | IACS-6274 |
Gene, Accession, CAS # | CAS: 1853164-83-6 |
Catalog # | 35855-5 |
Price | $448.00 |
Order / More Info | IPN60090 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |