Selonsertib from CAYMAN CHEMICAL COMPANY
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| Product Name | Selonsertib |
| Description | An ASK1 inhibitor (IC50 = 5.01 nM); decreases apoptosis and stellate cell activation in an in vitro 3D-human liver microtissue model of palmitic acid-induced NASH at 1 µM; sensitizes KB-C2 ABCB1-expressing epidermoid carcinoma cells to doxorubicin and paclitaxel; reduces hepatic necrosis and increases in serum TNF-α, IL-6, and CCL2 in a mouse model of LPS/D-galactosamine-induced acute liver failure at 15, 30, or 60 mg/kg |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | GS-4977|GS-4997 |
| Gene, Accession, CAS # | CAS: 1448428-04-3 |
| Catalog # | 20972-1 |
| Price | $57.00 |
| Order / More Info | Selonsertib from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY