NVP-BEZ235 from CAYMAN CHEMICAL COMPANY
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| Product Name | NVP-BEZ235 |
| Description | A dual inhibitor of class I PI3Ks and mTOR (IC50s = 4, 75, 7, and 5 nM, for p110α, - β, -δ, and -γ, respectively) and mTOR (IC50 = 20 nM); selective for these enzymes over a panel of kinases (IC50s = >10 µM for all); inhibits proliferation of, and induces apoptosis in, MCF-7, MDA-MB-468, SK-BR-3, and MDA-MB-361 breast cancer cells at 0.1 or 1 µM; reduces tumor growth in a U87MG mouse xenograft model at 25, 35, or 45 mg/kg |
| Size | 250 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Dactolisib |
| Gene, Accession, CAS # | CAS: 915019-65-7 |
| Catalog # | 10565-250 |
| Price | $235.00 |
| Order / More Info | NVP-BEZ235 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY