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Product Name | Nylidrin |
Description | An agonist of β-ARs and antagonist of NR1A/2B subunit-containing NMDA receptors; binds to β-adrenergic receptors (Kd = 0.37 µM) and activates adenylate cyclase (Ka = 1.3 µM); selective for NR1A/2B over NR1A/2A and NR1A/2C subunit-containing NMDA receptors (IC50s = 0.18, 32, and 42 µM, respectively); inhibits NMDA-induced responses in primary rat cortical neurons (IC50 = 0.22 µM); decreases blood pressure and increases heart rate in SHRs (MED = 0.5 mg/kg); inhibits influenza hemagglutinin 2-mediated membrane fusion in Vero E6 cells at 20 and 100 µM; inhibits infection of MDCK cells by H1N1 and H3N2 influenza isolates in vitro (EC50s = 7.2 and 12.1 µM, respectively) and prevents infection in a mouse model of mouse-adapted H1N1 infection |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Buphenine |
Gene, Accession, CAS # | CAS: 447-41-6 |
Catalog # | 33232-10 |
Price | $57.00 |
Order / More Info | Nylidrin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |