Edit |   |
---|---|
Product Name | (-)-Securinine |
Description | An alkaloid; reduces proliferation of SW480 colon adenocarcinoma cells in a dose- and time-dependent manner; decreases viability of HL-60 leukemia cells (IC50s = 47.88, 23.85, and 18.87 µM at 24, 48, and 72 hours post-treatment, respectively); induces cell cycle arrest at the G1/S phase and decreases PI3K, Akt, and mTOR gene expression in a dose-dependent manner; inhibits GABA and GABA-activated benzodiazepine binding to rat brain membranes (IC50s = 57 and 101 µM, respectively); induces clonic and tonic convulsions in mice at 5.2 mg/kg, |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | L-Securinine|NSC 107413 |
Gene, Accession, CAS # | CAS: 5610-40-2 |
Catalog # | 24902-10 |
Price | $81.00 |
Order / More Info | (-)-Securinine from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |