(-)-Securinine from CAYMAN CHEMICAL COMPANY
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| Product Name | (-)-Securinine |
| Description | An alkaloid; reduces proliferation of SW480 colon adenocarcinoma cells in a dose- and time-dependent manner; decreases viability of HL-60 leukemia cells (IC50s = 47.88, 23.85, and 18.87 µM at 24, 48, and 72 hours post-treatment, respectively); induces cell cycle arrest at the G1/S phase and decreases PI3K, Akt, and mTOR gene expression in a dose-dependent manner; inhibits GABA and GABA-activated benzodiazepine binding to rat brain membranes (IC50s = 57 and 101 µM, respectively); induces clonic and tonic convulsions in mice at 5.2 mg/kg, |
| Size | 100 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | L-Securinine|NSC 107413 |
| Gene, Accession, CAS # | CAS: 5610-40-2 |
| Catalog # | 24902-100 |
| Price | $356.00 |
| Order / More Info | (-)-Securinine from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY