GNE-2861 from CAYMAN CHEMICAL COMPANY
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| Product Name | GNE-2861 |
| Description | A group 2 PAK inhibitor (IC50s = 7.5, 126, and 36 nM for PAK4, -5, and -6, respectively); selective for group 2 PAKs over group 1 PAKs (IC50s = 5.42, 0.97, and >10 µM for PAK1, -2, and -3, respectively), as well as JAK3, KHS1, MAP4K4, and MINK1 at 1 µM; inhibits cell migration and reduces cell viability of MDA-MB-436 and MCF-10A PIK3CA cells from 0.1-50 µM; sensitizes drug-resistant MCF-7/LCC2 breast cancer cells to tamoxifen |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | GNE2861 p-21 p21activated PAK5 PAK6 PAK2 PAK3 PAK 4 1 JAK KHS MAP-4K4 MAP4K MINK MDAMB MDAMB436 MB436 MCF10A PIK-3CA PIK3-CA MCF7 LCC-2 |
| Gene, Accession, CAS # | CAS: 1394121-05-1 |
| Catalog # | 29458-5 |
| Price | $303.00 |
| Order / More Info | GNE-2861 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY