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Product Name | Koumine |
Description | An alkaloid with diverse biological activities; inhibits the proliferation of MCF-7 cells (IC50 = 124 µg/ml) as well as induces apoptosis and cell cycle arrest at the G2/M phase in the same cells; reduces LPS-induced increases in iNOS, IL-1β, IL-6, and TNF-α levels in RAW 264.7 macrophages at 200 and 400 µg/ml; inhibits acetic acid-induced writhing and formalin-induced paw licking and biting in mice at 2 and 10 mg/kg; increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity, at 0.4-10 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2223614-73-9 MCF7 IL6 IL1β TNFα RAW264.7 |
Gene, Accession, CAS # | CAS: 1358-76-5 |
Catalog # | 36210-1 |
Price | $89.00 |
Order / More Info | Koumine from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |