NAS-181 from CAYMAN CHEMICAL COMPANY
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| Product Name | NAS-181 |
| Description | A 5-HT1B receptor antagonist (Ki = 47 nM); selective for 5-HT1B over 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = >3,000 nM for all for the rat receptors); potentiates potassium-stimulated 5-HT release in isolated and preloaded rat occipital cortical slices at 100 or 1000 nM; increases extracellular levels of ACh, but not glutamate or GABA, in the frontal cortex and ventral hippocampus of non-anesthetized rats at 1, 5, or 10 mg/kg; induces wet-dog shakes in rats at 3 mg/kg, which can be prevented by p-chloro phenylalanine; increases the length of freezing time induced by contextual fear conditioning in mice |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 205242-61-1 205242-62-2 NAS181 5HT1B 5HT 5HT1A 5HT2A 5HT2C 5HT6 5HT7 extra-cellular nonanesthetized |
| Gene, Accession, CAS # | CAS: 1217474-40-2 |
| Catalog # | 39191-5 |
| Price | $248.00 |
| Order / More Info | NAS-181 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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