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Product Name | Rubitecan |
Description | A DNA topoisomerase I inhibitor; inhibits DNA topoisomerase I and increases the fraction of supercoiled DNA in a cell-free assay; inhibits the growth of A121 ovarian and H460 lung cancer cells (IC50s = 4 and 2 nM, respectively); inhibits the growth of doxorubicin-susceptible and -resistant MCF-7 breast cancer cells (IC50s = 2 and 3 nM, respectively); reduces tumor growth in a U937 leukemia mouse xenograft model at 4 mg/kg twice per week |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 9-nitro-20(S)-Camptothecin|RFS 2000 |
Gene, Accession, CAS # | CAS: 91421-42-0 |
Catalog # | 28956-10 |
Price | $49.00 |
Order / More Info | Rubitecan from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |