Edit |   |
---|---|
Product Name | GDC-0575 |
Description | A Chk1 inhibitor (IC50 = 1.2 nM); >30-fold selective for Chk1 over a panel of more than 450 wild-type and mutant kinases; enhances cytarabine-induced apoptosis in HL-60, KG-1, U937, and ML-1 AML cells; nearly completely eliminates tumor burden in AML PDX mouse models at 7.5 mg/kg in combination with cytarabine |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Chk HL60 KG1 U-937 ML1 GDC0575 |
Gene, Accession, CAS # | CAS: 1196541-47-5 |
Catalog # | 34300-5 |
Price | $145.00 |
Order / More Info | GDC-0575 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |