R 715 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY
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| Product Name | R 715 (trifluoroacetate salt) |
| Description | A bradykinin B1 receptor antagonist; inhibits bradykinin-induced contractions in isolated human umbilical cords, which express bradykinin B1 receptors (pA2 = 8.49); decreases the latency to tail withdrawal in the tail-flick test in an STZ-induced mouse model of diabetic neuropathy at 200, 400, and 600 µg/kg; reduces the incidence of hind limb weakness and paralysis, improves symmetrical gait, as well as decreases spinal inflammatory foci numbers, neuron demyelination, and lesion monocyte invasion, in a MOG35-55 peptide-induced mouse model of EAE at 1 mg/kg per day; reduces mean arterial blood pressure and increases heart rate in spontaneously hypertensive rats at 0.01 nmol/animal, i.c.v |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [Ac-Lys-[D-βNal7,Ile8]des-Arg9]-BK|Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-D2Nal-Ile-OH |
| Gene, Accession, CAS # | n/a |
| Catalog # | 36890-5 |
| Price | $1263 |
| Order / More Info | R 715 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY