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Product Name | NS 3623 |
Description | An ion channel modulator; inhibits the VRAC in HEK293 cells and chloride conductance in isolated human red blood cells (IC50s = 1.8 and 0.21 µM, respectively); activates hERG/Kv11.1 (EC50 = 79.4 µM) but does not activate Kv1.5, Kv4.3, or Kv7.1 at 30 µM; increases red blood cell density and improves red blood cell morphology in the SAD transgenic mouse model of sickle cell disease at 100 mg/kg per day for 21 days; reverses E-4031-induced QT interval prolongation in conscious guinea pigs at 50 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NS3623 gogo E4031 trans genic |
Gene, Accession, CAS # | CAS: 343630-41-1 |
Catalog # | 34992-5 |
Price | $112.00 |
Order / More Info | NS 3623 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |