N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide from CAYMAN CHEMICAL COMPANY
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| Product Name | N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide |
| Description | An inhibitor of HIF-1 signaling (IC50 = 0.32 µM in a cell-based HRE reporter assay under hypoxic conditions); inhibits hypoxia-induced increases in HIF-1α levels in MDA-MB-231, SKOV3, and HeLa cells in a concentration-dependent manner; inhibits hypoxia-induced VEGF expression and capillary-like tube formation in HUVECs; inhibits migration and invasion of MDA-MB-231 cells in wound healing and transwell assays under hypoxic conditions; reduces lung metastasis in an MDA-MB-231 mouse xenograft model at 15 and 30 mg/kg every other day |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | HIF1 HIF1α 1 α MB231 MDAMB MDAMB231 SKOV 3 Fluoro-phenethyl methoxy-phenyl |
| Gene, Accession, CAS # | CAS: 2380261-53-8 |
| Catalog # | 29740-5 |
| Price | $336.00 |
| Order / More Info | N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY