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Product Name | ITE |
Description | An endogenous AhR agonist; binds to AhR (Kd = 65 nM) and induces AhR-dependent transcription in luciferase reporter assays at 0.01 µM; inhibits anti-CD40- and IL-4-induced differentiation of isolated mouse splenic B cells, as well as proliferation and migration of SKOV3 ovarian cancer cells at 1 µM; reduces retinal detachment and ocular inflammatory cell infiltration in a mouse model of experimental autoimmune uveitis induced by CFA and M. tuberculosis at 200 µg/animal; reduces tumor growth by 39% in an OVCAR-3 mouse xenograft model at 80 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CD-40 IL4 Mycobacterium OVCAR3 SKOV-3 |
Gene, Accession, CAS # | CAS: 448906-42-1 |
Catalog # | 25355-5 |
Price | $51.00 |
Order / More Info | ITE from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |