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Product Name | Montelukast |
Description | A CysLT1 receptor antagonist (IC50 = 4.9 nM in HEK293 cell membranes expressing the human receptor); selective for CysLT1 over CysLT2 receptors (IC50 = >10,000 nM in COS-7 cell membranes expressing the human receptor); inhibits LTD4-induced bronchoconstriction in anesthetized guinea pigs (ED50 = 69 nmol/kg, p.o.); inhibits ovalbumin-induced airway hyperresponsiveness and increases in the number of total cells and eosinophils in BALF in a mouse model of allergic asthma at 3 and 10 mg/kg |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MK-476 |
Gene, Accession, CAS # | CAS: 158966-92-8 |
Catalog # | 35779-100 |
Price | $141.00 |
Order / More Info | Montelukast from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |