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Product Name | 4-Methylumbelliferone |
Description | A synthetic coumarin with diverse biological activities; inhibits hyaluronic acid synthesis in PC3-ML and DU145 cells (IC50s = ~0.4 mM for both); inhibits the growth of PC3-ML, DU145, C4-2B, LNCaP, and LAPC-4 prostate cancer cells (IC50s = 0.2-0.4 mM) and invasion and chemotactic motility of PC3-ML and DU145 cells in vitro; reduces tumor growth and microvessel density in a PC3-ML mouse xenograft model at 225 and 450 mg/kg twice per day; active against H. pylori and V. cholerae in vitro (MICs = 59 and 100-200 µg/ml, respectively); ex/em = 320 and 360 nm at low and high pH, respectively/455 and 445 nm at low and high pH, respectively. |
Size | 50 g |
Concentration | n/a |
Applications | Fluorescence |
Other Names | 4-Methyl-7-hydroxycoumarin|4-?U|7-Hydroxy-4-methylcoumarin|Hymecromone |
Gene, Accession, CAS # | CAS: 90-33-5 |
Catalog # | 29603-50 |
Price | $32.00 |
Order / More Info | 4-Methylumbelliferone from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |