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Product Name | TMP-195 |
Description | A class IIa HDAC inhibitor (Kis = 59, 60, 26, and 15 nM for HDAC4, 5, 7, and 9, respectively); selective for class IIa HDACs over class I and class IIb HDACs (Kis = 10-43 µM for HDAC1-3, 6, 9, and 10-11); blocks accumulation of CCL2 in the supernatant of CSF-1-stimulated monocytes; increases secretion of CCL1 by CSF-1 and GM-CSF-stimulated monocytes; reduces tumor burden and the number of pulmonary metastases in a macrophage-dependent autochthonous mouse model of breast cancer, |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | TMP195 HDAC2 HDAC3 HDAC5 HDAC6 HDAC7 HDAC9 HDAC10 HDAC11 CCL-1 2 CSF1 GMCSF HDAC-4 1 II-a b |
Gene, Accession, CAS # | CAS: 1314891-22-9 |
Catalog # | 23242-1 |
Price | $32.00 |
Order / More Info | TMP-195 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |