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Product Name | EC330 |
Description | A LIF inhibitor; binds to LIFR and is selectively cytotoxic to MCF-7 cells ectopically overexpressing LIF (IC50 = 0.075 µM) over non-LIF-overexpressing MCF-7 cells (IC50 = 0.245 µM); reduces ectopic LIF expression-induced increases in the migration of MCF-7 and MDA-MB-231 cells at 5 and 15 nM, respectively; induces ferroptosis in 293T and 786-O cells; reduces tumor burden to a greater extent in a mouse xenograft model using MDA-MB-231 cells with ectopic LIF expression than when using MDA-MB-231 cells without ectopic LIF expression |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | EC 330 MCF7 MDAMB231 MDAMB MB231 786O intra-cellular |
Gene, Accession, CAS # | CAS: 2016795-77-8 |
Catalog # | 37551-10 |
Price | $743.00 |
Order / More Info | EC330 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |