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Product Name | PRX-08066 |
Description | A 5-HT2B receptor antagonist; binds to 5-HT2B receptors (Ki = 3.4 nM); inhibits 5-HT-induced MAPK activation and thymidine incorporation in CHO cells expressing human 5-HT2B (IC50s = ~12 and ~3 nM, respectively); reduces peak pulmonary arterial pressure and right ventricular hypertrophy in a rat model of MCT-induced pulmonary hypertension at 50 and 100 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 866206-54-4 |
Gene, Accession, CAS # | CAS: 866206-54-4 |
Catalog # | 31477-10 |
Price | $431 |
Order / More Info | PRX-08066 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |