RK-287107 from CAYMAN CHEMICAL COMPANY
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| Product Name | RK-287107 |
| Description | A TNKS1 and TNKS2 inhibitor (IC50s = 0.014 and 0.010 µM, respectively); selective for TNKS1 and TNKS2 over PARP1, PARP2, and PARP10 (IC50s = >20, 2.7, and 19.8 µM, respectively); inhibits Wnt-dependent signaling (IC50 = 0.077 µM in a reporter assay); increases Axin2 accumulation in COLO 320DM cells at 0.1 µM; inhibits cell growth in COLO 320DM cells (GI50 = 0.45 µM); reduces tumor growth in a COLO 320DM mouse xenograft model at 150 mg/kg |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | RK287107 TNKS-1 2 PARP-1 2 10 Axin-2 COLO320DM 320-DM |
| Gene, Accession, CAS # | CAS: 2171386-10-8 |
| Catalog # | 30998-1 |
| Price | $68 |
| Order / More Info | RK-287107 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY