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Product Name | NS 13001 |
Description | A positive allosteric modulator of KCa2.2/SK2 and KCa2.3/SK3; increases calcium-induced currents in an inside-out patch clamp assay using HEK293 cells expressing human KCa2.2/SK2 or KCa2.3/SK3 (EC50s = 1.8 and 0.14 µM, respectively); improves sensorimotor deficits in the beam walk test and increases the latency to fall in the rotarod test in a SCA2-58Q transgenic mouse model of neuromuscular degeneration at 30 mg/kg per day, p.o. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NS13001 HEK-293 SCA258Q |
Gene, Accession, CAS # | CAS: 1063331-94-1 |
Catalog # | 37317-1 |
Price | $36.00 |
Order / More Info | NS 13001 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |