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Product Name | NVP-BAG956 |
Description | A dual PDK1 and class I PI3K inhibitor (IC50s = 245, 56, 446, 35, and 117 nM for PDK1, p110α, p110β, p110δ, and p110γ, respectively); inhibits phosphorylation of T308-PKB (IC50 = 45 nM) in and proliferation of U87MG cells (EC50 = 143 nM); induces cell cycle arrest at the G1 phase in MOLM-14 cells and reduces colony formation by patient-derived AML cells; reduces tumor burden in mice injected with 32D.p210-luc+cells when administered in combination with everolimus |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | BAG956 |
Gene, Accession, CAS # | CAS: 853910-02-8 |
Catalog # | 24195-10 |
Price | $231.00 |
Order / More Info | NVP-BAG956 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |