JTE-607 from CAYMAN CHEMICAL COMPANY

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Product NameJTE-607
DescriptionA cytokine synthesis inhibitor; inhibits the production of TNF-α, IL-1β, IL-6, IL-8, and IL-10 in LPS-stimulated isolated human PBMCs (IC50s = 11, 5.9, 8.8, 7.3m and 9.1 nM, respectively); binds to CPSF3 in cell-free assays; induces accumulation of CXCL8 pre-mRNA in LPS-stimulated SC cells; reduces LPS-induced mortality in a C. parvum-sensitized mouse model of endotoxic shock from 0.3-10 mg/kg, i.v.
Size25 mg
Concentrationn/a
Applicationsn/a
Other Names188791-71-1 JTE607 TNFα IL1β IL6 IL8 IL10 CPSF CXCL Cryptosporidium
Gene, Accession, CAS #CAS: 188791-09-5
Catalog #36942-25
Price$289.00
Order / More InfoJTE-607 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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