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Product Name | Urocortin (human) (trifluoroacetate salt) |
Description | A neuropeptide hormone; binds to type 1 and 2 CRF receptors as well as CRF-BP (Kis = 0.41, 1.8, 1.5, and 0.22 nM for human CRF1, rat CRF2α, mouse CRF2β, and human CRF-BP, respectively); induces cAMP production in CHO cells expressing human CRF1, rat CRF2α, and mouse CRF2β receptors (EC50s = 0.22, 0.32, and 0.13 nM, respectively); inhibits migration and proliferation of human VSMCs and reduces LDL-induced foam cell formation in vitro; slows development of aortic atherosclerotic lesions in Apoe-/- mice; decreases food intake in food-deprived and non-deprived rats as well as water intake in water-deprived rats in a dose-dependent manner |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | 176591-49-4 nondeprived CRF-1 2α 2β CRFBP low density lipoprotein |
Gene, Accession, CAS # | n/a |
Catalog # | 24744-500 |
Price | $219.00 |
Order / More Info | Urocortin (human) (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |